Scleraxis 翻译

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August undefined, 2024

Web1 Nov 2001 · Scleraxis is expressed in all axial and limb tendons. Expression of scleraxis in chick embryos at day 9 (stage 35; A,E,F) and day 10 (stage 36; B,C,D)of development , visualized by whole-mount in ... Web13 May 2024 · Scleraxis also induces Epithelial to Mesenchymal Transition (EMT) and cell migration as part of development and cell differentiation. Some studies have shown that mechanical stretch in tendons increases expression of scleraxis, while additional studies reported that stretch in rabbit aorta induces the vascular smooth muscle proliferative ...

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Webab58655 被引用在 44 文献中. Best KT et al. Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis. Elife 10:N/A (2024). PubMed: 33480357; Dede Eren A et al. Tendon-Derived Biomimetic Surface Topographies Induce Phenotypic Maintenance of Tenocytes In Vitro. Tissue Eng Part A 27:1023-1036 (2024). PubMed: … WebScleraxis-null mice are viable and have a range of tendon and bone defects in the trunk and limbs but no described cranial phenotype. We report the expression of zebrafish scleraxis orthologs: scleraxis homolog (scx)-a and scxb in cranial and intramuscular tendons and in other skeletal elements. Single mutants for either scxa or scxb, generated ... github配置ssh key

Scleraxis genes are required for normal ... - University of Bristol

Web中文翻译： MiR-6924-5p 丰富的外泌体源自转基因 Scleraxis 过表达 PDGFRα(+) BMMSCs 作为治疗腱骨愈合过程中的骨质溶解和提高愈合强度的新型纳米治疗剂肌腱-骨界面的骨质溶解会削弱肌腱-骨愈合过程中的拔出力，导致手术失败，但临床治疗效果并不理想。 It is thought that early scleraxis-expressing progenitor cells lead to the eventual formation of tendon tissue and other muscle attachments. Scleraxis is involved in mesoderm formation and is expressed in the syndetome (a collection of embryonic tissue that develops into tendon and blood vessels) of developing somites (primitive segments or compartments of embryos). Web28 May 2024 · Scleraxis is a basic helix-loop-helix transcription factor that plays a central role in promoting tenocyte proliferation and matrix synthesis during embryonic tendon development. However, the role of scleraxis in the growth and adaptation of adult tendons is not known. We hypothesized that scleraxis is required for tendon growth in response to ... github访问慢 hosts

The transcription factor scleraxis differentially regulates gene ...

Getting to the heart of myofibroblast differentiation: implications …

WebScleraxis has recently been identified as a basic helix-loop-helix transcription factor (12). Its mRNA is expressed in mouse embryos between days 9.5 and 10.5 post-coitum in sclerotomes and in mesenchymal cells of the body wall and limb buds. Subsequently, scleraxis is expressed at high levels within mes- WebDevelopmental stage. At 6.0-6.5 dpc, expressed throughout the egg cylinder with highest expression in the epiblast. At 9.5-10.5 dpc, expressed in the lateral sclerotome and in mesenchymal cells of the limb buds and body wall. At 11.0 dpc, expressed in a metameric pattern extending along the length of the embryo. github 镜像 git cloneWebmice with a targeted inactivation of scleraxis (Scx / mice), limb tendons fail to properly form, resulting in a severe reduction in mobility after birth.8 Injection of mesenchymal stem cells transduced with scleraxis into the injured rotator cuff muscles of rats improves heal-ing of the bone-tendon interface.10 Scleraxis continues github 镜像 fastgit

"Web23 Oct 2024 · The report published in a recent issue of the American Journal of Physiology-Heart and Circulatory Physiology by Al-Hattab et al. , “Scleraxis regulates Twist1 and Snai1 expression in the epithelial-to-mesenchymal transition,” represents the authors’ latest work in characterizing scleraxis as an essential regulator of myofibroblast differentiation and … " - Scleraxis 翻译

Scleraxis 翻译

Web1 Oct 2001 · Little is known about the genesis and patterning of tendons and other connective tissues, mostly owing to the absence of early markers. We have found that Scleraxis, a bHLH transcription factor, is a highly specific marker for all the connective tissues that mediate attachment of muscle to bone in chick and mouse, including the limb … WebLa proteína de la escleraxis es un miembro de la superfamilia básica de factores de transcripción hélice-bucle-hélice (bHLH) . [1] Actualmente dos genes ( SCXA y SCXB respectivamente) se han identificado con el código para las proteínas scleraxis idénticas.

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Web1 Sep 2024 · Together, these results indicate that scleraxis can regulate EMT via direct transactivation of the Twist1 and Snai1 genes. Given the role of scleraxis in also driving the myofibroblast phenotype, scleraxis appears to be a critical controller of fibroblast genesis and fate in the myocardium and thus may play key roles in wound healing and fibrosis. WebCharacterization of Scleraxis and SRY-Box 9 from Adipose-Derived Stem Cells Culture Seeded with Enthesis Scaffold in Hypoxic Condition MT翻译. 缺氧条件下脂肪源性干细胞培养的Scleraxis和Sry-box9的鉴定 ...

Web11 May 2007 · A recent study attempting to use Scleraxis regulatory elements to drive reporter gene expression in tendons has shown that a construct encompassing sequences 5′ to the Scx gene and only 1.8 kb of genomic sequence 3′to the Scleraxis gene was sufficient to drive expression in tendons, but not all tendons were labeled in these mice … Websclerosis 在英语-中文（简体）词典中的翻译. sclerosis. noun [ U ] medical specialized uk / skləˈrəʊ.sɪs / us / -ˈroʊ- /. a medical condition that causes body tissue or organs to …

Web22 Mar 2024 · Scleraxis (Scx) is a basic helix-loop-helix transcription factor that is expressed persistently in tendons/ligaments, but transiently in entheseal cartilage. Web2. Objective To prevent and treat the scleroses from intramuscular injection. 目的预防并治疗臀部肌内注射的硬结形成。. 3. There are two other forms of arteriosclerosis (hardening …

Web16 Feb 2024 · Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system. Scientific Reports (2024).

WebScx(Scleraxis)在肌腱发育成熟中起了非常重要的作用，是肌腱和韧带相对特异分子标志。本文就Scx的分子结构、在肌腱发育成熟中的作用及其调控机制进行综述。 github 的 ipWebScleraxis Antibody (A-7) is an IgG 2a κ mouse monoclonal Scleraxis antibody (also designated Scleraxis antibody) suitable for the detection of the Scleraxis protein of mouse, rat and human origin by WB, IP, IF and ELISA. Scleraxis Antibody (A-7) is available as both the non-conjugated anti-Scleraxis antibody form, as well as multiple conjugated forms of … github 自动 sync forkWeb10 Nov 2024 · Scleraxis(Scx)是已知的肌腱细胞标志物，通过构建Ctsk-Cre;Rosa26-ai9;Scx-GFP 报告小鼠，发现肌腱来源Ctsk+Scx+细胞是一群高表达肌腱干细胞标志物，且具有最强的克隆形成能力和三向分化能力的肌腱祖细胞。 furnisher credit reportsWeb21 Nov 2024 · 研究 2024-11-21 20:10 来源： Biomaterials：基于Scleraxis过表达的工程化BMMSC来源外泌体的纳米疗法可抑制腱骨界面骨溶解并提高腱骨愈合强度已关闭评论 3 在一些常见的运动系统损伤，例如前叉韧带损伤、肩袖损伤等发生后，往往需要手术重建腱-骨连接部，以便恢复患者运动功能。 furnisher couch typesWebExpression of scleraxis, tenomodulin and aggrecan was similar between all cell types. This study represents a characterization of tenocyte-like cells from the human rotator cuff as close as possible. It helps analyzing their biological properties and allows further studies to improve production of tendon matrix and furnish equipmentWebScleraxis Antibody (A-7) is an IgG 2a κ mouse monoclonal Scleraxis antibody (also designated Scleraxis antibody) suitable for the detection of the Scleraxis protein of mouse, rat and human origin by WB, IP, IF and ELISA. Scleraxis Antibody (A-7) is available as both the non-conjugated anti-Scleraxis antibody form, as well as multiple conjugated forms of … furnisher badWebScleraxis (Scx) is a basic helix-loop-helix (bHLH) transcription factor that is regulated by TGFβ signaling and is required for the proper embryonic development of tendons (8, 9). Scleraxis is the earliest detectible marker for differentiated tendon cells (10), and activates furnisher definition